Exploring the progression of drug dependence in a methamphetamine self-administration rat model through targeted and non-targeted metabolomics analyses

Abstract Persistent neurochemical and biological disturbances resulting from repeated cycles of drug reward, withdrawal, and relapse contribute to drug dependence.Methamphetamine (MA) is a psychostimulant with substantial abuse potential and neurotoxic effects, primarily affecting monoamine neurotransmitter systems in the brain.In this study, we ai

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The State non-contractual liability because of forced displacement of persons (Setting up a line of case law in State council decisions)

Initially the theory of repairing the damage caused by act or omission attributable to the state as a subject faced ROOIBOS the dogma of irresponsibility.This was a paradigm that in the context of the new constitutional law should not be allowed any validity because it is not a case of the exercise of a divine power or Leviathan because of its supe

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